Reflections on Revolutionary Change

Regime Change and Revolutionary Entrepreneurs

Istudy how a revolutionary vanguard might use violence to mobilize a mass public. The mechanism is informational—–the vanguard uses violence to manipulate population member’s beliefs about the level of antigovernment sentiment in society. The model has multiple equilibria, one equilibrium in which there may be revolution and another in which there is certain not to be. In the former, structural...

CIO Turnover, IS Alignment and Revolutionary Change

Information systems (IS) alignment is an important aspect in using information technology to gain business value. A critical part of this process is the existence of a good relationship between the CEO and CIO. However, this relationship is disrupted due to CIO turnover. Using a punctuated equilibrium model perspective, this study examines the organizational impact of CIO turnover and its effec...

The more things change ... reflections on midwifery.

CIHR Health System Impact Fellows: Reflections on “Driving Change” Within the Health System

Learning health systems necessitate interdependence between health and academic sectors and are critical to address the present and future needs of our health systems. This concept is being supported through the new Canadian Institutes of Health Research (CIHR) Health System Impact (HSI) Fellowship, through which postdoctoral fellows are situated within a health system-related organization to h...

Revolutionary change in rheumatoid arthritis management with biological therapy.

Biological agents targeting a specific molecule have extraordinarily fine specificity and powerful functional capabilities. By the introduction of biological therapy, management of rheumatoid arthritis has undergone a revolution and a paradigm shift. In this review, I will summarize the role in the pathogenesis of rheumatoid arthritis of the molecules targeted by biologi...